Horseshoe crabs are older than the dinosaurs. They’ve been around for 450 million years, which means they watched the rise and fall of millions of
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As well as being incredible ‘living fossils’, they have also helped to keep most of us alive. If you have ever had a vaccine, chances are that it was
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Horseshoe crab blood is bright blue. It contains important immune cells that are exceptionally sensitive to toxic bacteria. When those cells meet
invading bacteria, they clot around it and protect the rest of the horseshoe crab’s body from toxins.
Scientists used these clever blood cells to develop a test called Limulus Amebocyte Lysate, or LAL, which checks new vaccines for contamination.
This technique has been used all over the world since the 1970s to stop medical professionals giving out jabs full of bad bacteria that could make
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It’s great for humans, because vaccines save us from all sorts of unwanted diseases, including measles and mumps. It’s not so great for the
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Horseshoe crabs and Covid
The world is rushing to find a safe vaccine to fight Covid-19, the viral lung disease which has swept the planet. Buy live horseshoe crab
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In many parts of the world, researchers will be relying on horseshoe crab blood in those important tests. And since we’ll want to vaccinate millions
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Why we should care
There are four species of horseshoe crab. Three of them live in Asia, around the coasts of India, Vietnam, China, Borneo and southern Japan. These
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The fourth is the American horseshoe crab (Limulus polyphemus) which lives along the east coast of North America, with a particularly large
number going to the beaches of the Delaware Bay to mate each year.
These crabs may look prehistoric, but they do an important job of supporting other animals around them: their eggs are a nourishing snack for
migrating birds. They are also good for fishermen because they help keep the sediment around coastlines healthy.
The International Union for the Conservation of Nature (IUCN) says, ‘The horseshoe crab is a critical link to coastal biodiversity. One of their
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But living alongside humans can be difficult for horseshoe crabs. They are often used as fishing bait. In Asia, they are also harmed by pollution,
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Some die after being bled for medical testing, although we don’t know how many. Plus, lots die because they strand upside down on beaches after
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For years, no one managed to find any alternative ingredients to use in a test that were as sensitive as crabs’ blood.
But there is hope: in the late 1990s biologists at the University of Singapore realised that a synthetic alternative could be created in a lab by cloning
a molecule in the crab blood. This genetically engineered protein is called Recombinant Factor C, or rFC.
Some governments, including the Japanese and Chinese, have approved the rFc test for use. It is likely that a new Covid test manufactured in the
UK will use synthetic ingredients, which are also approved by the European Union. Pfizer, a pharmaceutical company developing one of the
biggest potential Covid vaccines, said they won’t be using crab blood in their jab.
There’s a catch in this story. Synthetic ingredients and alternative tests are not yet widely used in some countries. For instance, America still bleeds
many crabs every year. A small percentage of them die after being bled, although medicine producers are becoming ever more careful about
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It’s also arguable medicine manufacturers aren’t the biggest problem facing horseshoe crabs: in America many more are killed for fishing bait and
lots are struggling in Asia because their habitat is disappearing. best buy horseshoe crabs is grown in farms or found in wild.
Will horseshoe crabs go extinct?
The American horseshoe crab is not considered endangered (although it is classified as vulnerable on the IUCN Red List of Threatened Species) and
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American regulators and manufacturers also created guidance on how to reduce the number of crabs killed during the bleeding process, which is
helping. Some crab populations are now increasing, although others are still struggling.
Some medicine companies have started sustainability programmes that rescue eggs from crabs that have been caught for bait. The eggs are
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The story in Asia is less promising. Crab mating grounds are being destroyed more quickly by rising sea levels and building work. The tri-spine
horseshoe crab is classified as endangered. It is locally extinct in Taiwan, and may soon disappear from Hong Kong. The other two Asian horseshoe
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In 2019 the IUCN and other conservation groups around the world called for stronger rules to protect horseshoe crabs, more scientific research, and
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There is hope yet – and it perhaps won’t be long until we can phase out the use of crab blood for good.
The American horseshoe crab is a common sight on Florida’s beaches. Horseshoe crabs are “living fossils” meaning they have existed nearly
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Horseshoe crabs are not actually crabs at all, they are much more closely related to spiders and other arachnids than they are to crabs or lobsters!
There are four species of horseshoe crabs still around today. Only one species, Limulus polyphemus, is found in North America along the Atlantic
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Despite existing for hundreds of millions of years, horseshoe crabs are nearly identical to their ancient relatives. This is because their body structure
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Horseshoe crabs have a tank-like structure consisting of a front shell called the prosoma, a back shell called the opisthosoma, and a spike-like tail
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horseshoe crabs are just clumsy and they use their tail to flip themselves back over if they get overturned by a wave.*
Though the horseshoe crab’s shell is hard, it is very sensitive to the world around it. The crabs are especially sensitive to light. They have 10 eyes, a
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*Never pick up a horseshoe crab by its tail, as it can harm the animal. Instead, gently pick it up by both sides of the prosoma using both hands.
Horseshoe crabs are known to gather in large nesting aggregations, or groups, on beaches particularly in the mid-Atlantic states such as Delaware,
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When mating, the smaller male crab hooks himself to the top of the larger female’s shell by using his specialized front claws, and together they
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Some males (called satellite males) do not attach to females but still have success in fertilizing the female’s eggs by hanging around the attached
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Horseshoe crab larvae emerge from their nests several weeks after the eggs are laid. Juvenile horseshoe crabs look a lot like adults except that
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Why are horseshoe crabs important?
Horseshoe crabs are an important part of the ecology of coastal communities. Their eggs are the major food source for shorebirds migrating north,
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Horseshoe crabs are also extremely important to the biomedical industry because their unique, copper-based blue blood contains a substance
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This compound coagulates or clumps up in the presence of small amounts of bacterial toxins and is used to test for sterility of medical equipment
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Horseshoe crabs are also used in several fisheries. The marine life fishery collects live horseshoe crabs for resale as pets in aquariums, research
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